◇◇新语丝(www.xys.org)(xys.dxiong.com)(xys.freedns.us)(xys-reader.org)◇◇ 欣赏一下张阳德主任亲笔写的履历 ·方舟子· 最近中南大学湘雅医院外科主任张阳德击败众多竞争者获得主持1.2亿元 的863计划纳米医药项目，被人爆出官学勾结的黑幕，也引起了我的兴趣。我偶然 在张阳德担任主任的卫生部肝胆肠外科研究中心的网站见到张阳德一份详细的 英文个人履历： http://www.nhec.gov.cn/EN_lingdao.htm 它是用第一人称叙述的，可知是张主任的亲笔。这份用中式英语写成的履历 有不少有趣之处值得鉴赏。略举如下： 1987-1991 Obtained PH. D., Biomedical Engineering, U.S.A. 翻译过来就是：1987到1991年间，在美国获得生物医学工程博士学位。但是 没有按惯例注明是哪所美国大学。这倒新鲜了，因为在张阳德的中文简历中，从 没有见到他在美国留学并获得学位的介绍，而从他的经历看，他也没有在美国全职 留学的时间。就在同一份履历上，也写着在那个时间段，他是湘雅医院外科医生、 教授。难道张阳德在职读了个美国大学博士？不知有哪所美国大学有这样的项目？ 张主任能不能具体地说明一下他究竟是美国哪所大学的生物医学工程博士？可别 是著名的巴灵顿大学吧？ 张主任在美国的奇遇还不只这一点。再看： 1996.2-Current Visiting professor, National Cancer Research Center, National Institute of Health, U.S.A 翻译过来就是：1996年2月至今，为美国国家卫生院国家癌症研究中心的访问 教授。这也很新鲜：第一，美国国家卫生院不是大学，我不知道他们还会从国外 聘请访问教授，而且是长期聘请！第二，美国国家卫生院根本就没有“国家癌症 研究中心”这么个机构。不知张主任究竟去了美国的什么机构当访问教授？ 还有呢： 1999-Current Chief editor, “Endoscopy and Radiology”, U.S.A. 翻译：1999年至今，担任美国“Endoscopy and Radiology”杂志的主编。 以张主任的资质，能担任美国学术刊物的主编，也算得上奇遇。但是且慢，就在 同一个网站上，有中国卫生部肝胆肠外科研究中心招收“博士后学生”的英文告示， 里面有这么一句话： “Endoscopy and Radiology”(English version) is also edited by our unit. 也就是说，这份“Endoscopy and Radiology”英文刊物其实是中国卫生部肝 胆肠外科研究中心办的，难道中国卫生部的研究中心搬到到美国去了？ 张阳德担任的国际学术机构的领导职务可真不少，例如： Vice-president, International Endoscopist Association (U. S. A.) 即美国国际内窥镜医生协会副主席。我很想了解这个协会的情况，看谁比 张教授还牛，敢当他的正主席。google了一下"International Endoscopist Association"， 出来的就只有张阳德履历这么个网页。是不是该协会的成员都不好意思把它写进履历 中？ Vice-president, US-Asian International Exchange Foundation 这个头衔更大：美国－亚洲国际交换基金会副主席。google了一下，出来的还 是只有中国卫生部肝胆肠外科研究中心网站的网页。 Director, Committee of Japanese Explosive Association 这个头衔太吓人了：日本炸药协会委员会主任？张教授还在日本搞爆破？赶快 google，还是这个网页。 Director, Committee of International Explosive Association, U.S.A. 这是改到美国搞爆破了：美国国际炸药协会委员会主任。不怕被当成恐怖分子 抓起来？张主任访美时敢用这个头衔吗？同样，google的结果，还是回到这个网页。 Director, Committee of International Hepatobiliary & Enteric Surgery Association (Britain) 这个是英国国际肝胆肠外科协会委员会主任。看来与张教授的专业倒比较相符。 可惜，与该英国协会有关的，还是只有这个中国网页。 看来张教授的专业就是到各国去注册只有他一个成员的国际协会啊？这倒不需要 花多少钱，1.2亿元肯定是用不完的。剩下的钱怎么办？ 另外，张主任在这份英文履历中列出了他发表的几篇论文，居然没有一篇是在 国外的刊物上发表的。不知张主任在美国的博士是怎么读的，他的国际声誉是怎么 来的？靠1.2亿元堆出来的？ 附：卫生部肝胆肠外科研究中心张阳德主任的英文履历 Name: Zhang Yangde Sex: Male Nationality: Chinese Working Unit: National Hepatobiliary & Enteric Surgery Research Center, Ministry of Health, P.R.China Tel: 86-731-4327991 4327939 Mobile Phone: 86-13907310192 Fax:86-731-4327987 4327993 E-mail: ZYD@2118.cn Address: 87 Xiangya Road, Changsha, Hunan, P.R.China Working Position: Director National Hepatobiliary & Enteric Surgery Research Center, Ministry of Health, P. R. China Director National Key Laboratory of Nanobiological Technology, Ministry of Health, P. R. China President Institute of Biomedical Engineering, Central South University Director Department of Surgery, Xiangya Hospital, Central South University Director Organ Transplantation Center, Central South University Chief Editor “China Journal of Endoscopy” Chief Editor “China Journal of Modern Medicine” Chief Editor “Chinese Medical Engineering” Working Experience 1978.9-1990 Resident, attending doctor, associate professor, Professor, Department of Surgery, Xiangya Hospital, Hunan Medical University 1989-Current Chief editor, “China Journal of Endoscopy”, “China Journal of Modern Medicine” and “Chinese Medical Engineering” 1987-1991 Obtained PH. D., Biomedical Engineering, U.S.A. 1991.3-1991.12 Studied in Stockholm, Sweden 1994.7-Current Director and doctoral advisor, National Hepatobiliary & Enteric Surgery Research Center, Ministry of Health, P. R. China 1995 Did collaborative researches in State Biotechnology Research Center, Cuba, for 6 months 1996.2-Current Visiting professor, National Cancer Research Center, National Institute of Health, U.S.A 1996-1997 Did collaborative researches with institutes in Spain, Sweden, Britain and Germany 1999-Current Chief editor, “Endoscopy and Radiology”, U.S.A. 2000-Current President, Institute of Biomedical Engineering, Central South University 2001-Current Director, Department of Surgery, Xiangya Hospital, Central South University Director, Organ Transplantation Center, Central South University 2001-Current Expert-in-chief, Expert committee of National “the Tenth Five-year Plan” 863 program’s subject (the special subject of nanobiology, drug sieve and establishment of animal models) Biomedicine expert, Committee of National Key Programs of Nanotechnology 2002.10-Current Director, National Key Laboratory of Nanobiological Technology, Ministry of Health, P. R. China 2003.6-2003.8 Visited Germany and did clinical researches on artificial liver Positions in national and international academic organizations President, Endoscopist Branch of Chinese Medical Doctor Association Vice-president, International Endoscopist Association (U. S. A.) Vice-president, US-Asian International Exchange Foundation Director, Committee of Japanese Explosive Association (Researching on micro-explosion of biliary calculi) Director, Committee of International Explosive Association, U.S.A. (Researching on directed micro-explosion of biliary calculi) Director, Committee of International Hepatobiliary & Enteric Surgery Association (Britain) Director, Chinese Medical Association Committee director, Hunan Endoscopy Committee, Chinese Medical Association Committee director, Hunan Surgery Committee, Chinese Medical Association Research in cross-disciplines After clinical medical education in China, I received systemic education of science and engineering in United States, laid solid foundation of science and engineering which makes it better to combine medicine with engineering and bring different thoughts together. Untaken Key Research Programs: 1. Key scientific and technological tackled subject of “the Tenth Five-year Plan”: Research of autofluorescence analysis of early colorectal cancer under endoscopes 2. Program of NIH, U.S.A.: Sequencing research of 1 Kb DNA compounded by heat circulation method 3. National “the Ninth Five-year Plan” 863 Program: Research on transplantation of microcapsuled and gene-modified liver cells. 4. Sino-Cuban Key Program of Scientific and Technological Collaboration: Diagnosis research of laser-induced autofluorescence analysis of early colorectal cancer under endoscopes 5. Program of US-Asian International Exchange Foundation: Image analysis and scan techniques under colonoscopes 6. Clinical Key Construction Program of Ministry of Health, P.R.China: Research of treating nexcisable liver cancer by isolating liver perfusion 7. Sino-Cuban collaborative program: Research on pharmacodynamics of Cholesolvin 8. Hunan Scientific and Technological Tackled Key Program: Diagnosis system of laser-induced autofluorescence analysis of early colorectal cancer 9. National “the Tenth Five-year Plan” Scientific and Technological tackled Plan: Intelligent electroscope and image processing system under endoscopes 10. National “the Tenth Five-year Plan” Scientific and Technological tackled Plan: New craft and corresponding nanopreparation of drawing activity flavone and ester terpene by propolis 11. National “the Tenth Five-year Plan” Nanomaterial of 863 Program and Great Project of Electric System of Computer: Nanobioactive material for tissue engineering 12. National “the Tenth Five-year Plan” 863 Program: Treating liver malignant tumors by magnetic nanodrug carriers Four achieved clinical breakthroughs: Developed the technology of directed micro-explosion of biliary calculi under colonoscopies Researched and developed a laser-induced autofluorescence endoscopic diagnosis system of early colorectal cancer Treatment of liver cancer with nanodrug carriers Developed a biodegraded nanobone materials collaborated with an institute in U.S.A. Mainly received awards: 1. Micro-explosion of biliary calculi: the first prize of scientific and technological progress of Hunan Province; an outstanding prize of achievements of the national natural science fund. It was proven to an initial move in this field. 2. Laser-induced autofluorescence endoscopic diagnosis system of early colorectal cancer: the first prize of scientific and technological progress of Hunan Province 3. Research on TaqDNA polymerase : the first prize of medical progress prize in science and technology of Hunan Province; the second prize of scientific and technological progress of Hunan Province 4. Effects and protection of blocked blood streams into liver on patients: the second prize of scientific and technological progress of Hunan Province Mainly received patents: 1. Production of nanodrug carriers Patent No.: 02114356.0 2. Bioactive nanobone materials Patent No.: 02114355.2 3. Production of Microcapsuled liver cells Suspension Patent No.: 02114357.9 4. Explosion triggering gun Patent No.: 88218289 5. Pipes used for treating the biliary tract Patent No.: 8921931.4 6. Racking machine that can let the test tube be irritated into the liquid automatically Patent No.: 1212082.7 7. Multi-functional suction apparatus Patent No.: 92231031.5 8. Air-cooled and lamp-heated PCR instrument Patent No.: 94171022.3 9. Water jet scalpel Patent No.: 942310519 10. Xiao Jianzhong instant granules Patent No.: 94113186.6 11. Jing Chang powder Patent No.: 94113187.4 12. Compound konjaku tablet Patent No.: 94113188.2 13. Laser-induced autofluorescence diagnosis instrument of early colorectal cancer Patent No.: 97108217.0 14. Production method of two-way immune modifer Patent No.: 98112544.1 15. Preparation method of galactose Albumin Patent No.: 200410046676.0 16. Preparation method of adriamycin-polybutylcyanoacrylate nanoparticles Patent No.: 200410046648.9 17. Preparation method of galactose Albumin magnetic Adriamycin nanoparticles Patent No.: 200410046650.6 18. Preparation method of polybutylcyanoacrylate nanoparticles Patent No.: 200410046649.3 19. Preparation method of Albumin nanoparticles Patent No.: 200410046676.0 20. Preparation method of galactose alginic acid- Poly-1-lysine nanoparticles Patent No.: 200410046679.4 21. Preparation method of galactose hydroxyapatite-calcium phosphate-Poly-1-lysine nanoparticles Patent No.: 200410046678.X Clinical Surgery At the end of 1980s, I studied the clinical application of endoscopy thoroughly and systematically in American, and introduced them into China. Nowadays, the clinical application of endoscopy and mini-invasive operation have been widely adopted around China, which proved the assumption of successfully finishing multi-organ operation by endoscopy without being surgically operated. In 1994, the national training base of endoscopy----National Hepatobiliary & Enteric Surgery Research Center was founded. Till today, the laparotomy operation has completed for 1,1000 case. In 1995, China Journal of Endoscopy, which is the key national journal of clinical endoscopy, was published. In 1997, “Endoscopics”, which was the first national monograph of clinical endoscopy, was published by People’s Health Press, of which I was chief director in charge. Translated the authorized monographic book “Surgical Study on Laparotomy Operation” published in America. Edited three collections teaching materials of ministry of health, “Endoscopy of Enteron”, and won the third prize awarded by General Administration of Press and Publication and the 4th National Excellent Educational Video Product by Ministry of Education. Led the study of clinical endoscopy in China and is the vice chairman of the International Endoscopist Association. In 1997, I successfully finished the first operation in treating unexcisable late phase liver caner by the method of isolating liver perfusion in China. In 2004, I was named as the chairman of endoscopist association that affiliated to Chinese Medical Doctor Association, and presided the assessment and examination of endoscopist’s qualification license. At the end of 2001, I successfully operated on orthotopic auxiliary liver transplantation, in which the livers of patients were with multi-organs dysfunction. In 2004, I edited two books that are “Bioinformatics” and “Nanobiotechnology”, both were published by Science Press. Recently, study on curing tumors combined with effects of magnetic nanoparticles and Hypothermia. Teaching Achievements Supervising Doctors of Surgery, Masters of Surgery, Postdoctors of Surgery. Supervising Doctors of Biomedical Engineering, Master of Biomedical Engineering, Postdoctors of Biomedical Engineering. Mainly being charged with in the teaching of “Surgery” for undergraduates of 5-years and 7-years program. Mainly being charged with teachings of “Endoscopics”, “Bioinformatics” and “Nanobiotechnology” for 7-years graduate students. Publications In total, there are 6 monographs and 141 papers. 1. Theory and application of Polymerase Chain Reaction. Hunan Science and Technology Press, Changsha, 1994 2. Clinical prescription menu for doctor. Chemical Industrial Press, Beijing, 1998 3. Endoscopy. People’s Health Press, 1999 4. Biological Informatics. Science Press, Beijing, 2004 5. Nanobiological Technology. Science Press, Beijing, 2004 6. Chief translator of the authorized monographic book “Surgical Study on Laparotomy Operation” published in America, 2001 7. Edited three collections teaching material of heal ministry “Endoscopy of Enteron”, and won the third prize awarded by General Administration of Press and Publication and The 4th National Excellent Educational Video Product by Ministry of Education. 8. Zhang Yangde, Wang Guangsuo, Pan Yifeng, et al. Studies of targeting effects of lactosaminated nanoparticle gene carrier on liver. J Med Eng, 2002; 10(6): 12-16 9. Zhang Yangde, Gong Liansheng. Preparation and properties of magnetic Albumin nanoparticles containing Adriamycin. China Journal of Modern Medicine. 2001; 11 (3): 1-3 10. Zhang Yangde, Liu Jinbo. Involvement of studying polyisohexylcyanoacrylate nanoparticles. China Journal of Modern Medicine. 2003, 13(4): 31-35 11. Zhang Yangde, Ma Ren, He Jiantai, et al. The treatment of acute liver failure by using transplanted microencapsulated syngeneic, allogeneic and xenogeneic hepatocytes. Chin J Surg. 2001;18(1): 47-49 12. Zhang Yangde, Xu Yumin, Peng Jian. Viability and histological changes of encapsulated rat hepatocyte after transplantaion. Chin J Organ Transplant. 2001; 22(3):161-163 13. Zhang Yangde, Tang Guilin, Liu Weidong, Peng Jian. Differences in laser—induced autofluorescence between normal and carcinomatous colorectal tissues. Chinese Journal of Laser Medicine & Surgery. 2001;10(4): 205-209 14. Zhang Yangde, Peng Jian. Magnetic Albumin nanoparticles containing Adriamycin– An effective method on anti-tumor system. China Journal of Modern Medicine. 2001; 11(3): 39-42 15. Zhang Yangde, Peng Jian, Qin Jianmin. The effect of NO precursor or NOS inhibitor on survival of rats with acute liver failure. Chin J Gen Surg. 2001; 16 (11): 685 Chief Editor of Founded Journals 1. China Journal of Endoscopy, monthly published. 2. China Journal of Modern Medicine, half-monthly published. 3. China Medical Engineering, monthly published. Honors 1. Science and Technology Prize of Chinese Youth 2004 2. Outstanding Teacher of Hunan Province 2004 3. Pioneer of National Health System 2004 4. First Outstanding Experts of Hunan Province 2002 5. Excellent Studying Returnee of Hunan Province Jan, 1999 6. American World Award for Achievement Oct, 1996 7. One of the First 100 Stars of Medical Science and Technology in China Feb, 1995 8. Award of Brilliancy of Sci-Technology by Ministry of Science and Technology Dec, 1994 9. Precursor of National League of Young People Dec, 1992 10. Middle-Youth Age Outstanding Expert of P.R. China Nov, 1991 11. Specific Governmental Allowance by State Department Oct, 1990 12. Switzerland Ambitious Great Person Dec, 1989 13. Outstanding Expert of Ministry of Health Oct, 1988 (XYS20070911) ◇◇新语丝(www.xys.org)(xys.dxiong.com)(xys.freedns.us)(xys-reader.org)◇◇