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Æä´Î£¬ÎÒ²»ÖªµÀÕâ´Î²É·ÃÊÇͨ¹ýʲôÑùµÄÊֶεģ¬²»¹ýÓÐÒ»µãÎÒ ±íʾ²»½â£¬Ò»°ãÀ´Ëµ£¬ÐÂÎÅ·¢ÑÔÈ˶¼ºÜÄÑÖªµÀ±¾Ò½ÔºµÄÿ¸öÒ½Éú ÔÚ×öЩʲô¡£¿´ÁËÄǸöÐÂÎÅ·¢ÑÔÈ˵Ļش𣬺ÃÏóËû(Ëý)Ò²ÊÇÕâ·½ ÃæµÄר¼ÒËƵġ£ÎÒ»³ÒÉÕâ´ó¸ÅÓÐÁ½ÖÖ¿ÉÄÜ£¬µÚÒ»£¬ÄǸöÐÂÎÅ·¢ÑÔ ÈËÊdzÂÏþÄþÇ×½üµÄÈË£¬Ëû¶Ô³ÂÏþÄþ×öµÄ¿ÎÌâÁËÈçÖ¸ÕÆ£¬Õâ¸öÐÂÎÅ ·¢ÑÔÈËÒ²²»ÅųýJulie Korenberg. µÚ¶þÖÖ¿ÉÄÜ£¬ÄǸöÐÂÎÅ ·¢ÑÔÈËȷʵÊÇרְµÄ·¢ÑÔÈË£¬ÄÇô£¬¿ÉÒÔ˵£¬ÕâЩ²É·Ã¼ÊÇͨ¹ý ¾«ÐÄ×¼±¸µÄ¡£ÎÒ¿´ÓÐЩ»Ø´ðºÜÇÉÃ°ÑÖØÒªµÄÎÊÌâºöÂÔÒ»±ß¡£²» ÊÇÏÖ³¡¾ÍÄܻشðµÄ¡£¿Ï¶¨ÔÚ±³ºó×öÁ˺ܶàÑо¿£¬¸ãÁ˺ܶàµÄ¶Ô²ß¡£ ÕâÒ²¾ÍÊÇΪʲô½ðÁ¦½ÌÊÚ»¶Ó­´ó¼ÒÈ¥²É·ÃCedars-SinaiÒ½ÔºµÄ Ô­Òò°É. ÄÇô£¬Ä¿Ç°ÎÒÃÇÄÜ×öЩʲôÄØ? ÎÒÃÇÕÒ²»µ½Cedars-Sinaiҽѧ ÖÐÐĺÍJulie KorenbergÒÔ¼°³ÂÏþÄþŮʿµÄcompetitor,ÎÒÃÇ ¿ÉÒÔ´ÓÁíÍâÒ»¼Òµ¥Î»×ÅÊÖ¡£ ÄǼҵ¥Î»¾ÍÊÇÂåÉ¼í¶¼ÓÖÝ´óѧ¶ù¿Æϵ¡£ ÕâÊÇÏÖÔÚĿǰΨһÄÜÈóÂÏþÄþ¸Ðµ½×Ô¼ºÈõµãµÄµØ·½¡£²É·ÃµÄÎÊÌâ ´ó¸ÅÈçÏ£º 1. Èç¹ûÒ»¸öUCLAµÄadjunct associate professorÔÚÍâÃæ ×Ô³ÆΪassociate professor ÊÇ·ñºÏÊÊ? <¹À¼Æ»Ø´ð£º ²»Ì«ºÏÊÊ> 2. Èç¹ûUCLAµÄadjunct associate professorÔÚÍâÃæ×Ô³Æ Îªassociate professor,¶ù¿ÆϵÊÇ·ñÓÐÔðÈξÀÕýÕâ¸ö´íÎó? <¹À¼Æ»Ø´ð£ºÓ¦¸ÃÓÐÔðÈξÀÕýµÄ¡£> 3. ¿ÒÇëUCLA֪ͨ³ÂÏþÄþŮʿ£¬ÔÚËýµÄÖ÷Ò³ÉÏÐÞ¸ÄËýµÄtitle,Ϊ adjunct associate professor <¹À¼Æ»Ø´ð£ºUCLA¶ù¿ÆϵӦ¸Ã»á֪ͨÏþÄþŮʿµÄ> 4. ÓÐÁËÕâЩÐж¯ÒÔºó£¬ÔÙÈ¥²É·ÃCedars-SinaiҽѧÖÐÐÄ£¬ÎÊ£º ÄãÃÇҽѧÖÐÐĵÄÏþÄþŮʿ°Ñ×Ô¼ºµÄtitle¶¨Îªassociate professor£¬Õâ¼þÊÂÇéÊÇ·ñÇ¡ µ±? Äã¶ÔËýµÄÕâÖÖ×÷ΪÓÐʲôÆÀ¼Û? ...... ÏÖÔÚµÄÎÊÌâÊÇ£¬ÎÒÃÇҪŬÁ¦·¢ÏÖ³ÂÏþÄþ¿Í¹ÛÉϵÄÈõµã¡£ÍøÉÏ´ó¼Ò¶¼ ¶ÔÄǸöBACµÄÎÄ¿â¼ÛÖµ¾À²øÀ´¾À²øÈ¥£¬ÎÒ¿´ÊÇûÓнá¹ûµÄ£¬´ó¼Ò¸ã Ñо¿Õâô¶àÄêÁË£¬Ò²ÖªµÀÑо¿Ò²¾ÍÊÇÕâôһ»ØÊ£¬°ÑÖ¥Âé´óµÄÒ»µã ÊÂÇé´µ³ÉÁËÎ÷¹Ï¡£ËùÒÔÎÊBACÎÄ¿âµÄ¼ÛÖµÓжà´ó£¬ºÜÄÑÓÐÒ»¸ö¹«Õý µÄ»Ø´ð¡£ÒòΪÑо¿ÕⶫÎ÷£¬ÊǷdz£Ö÷¹ÛµÄ¶«Î÷¡£ÎÒÃÇÖ»ÄÜ´Ó³ÂÏþÄþ ¿Í¹ÛÉϵÄÈõµã×ÅÊÖ£¬ÕâÑù²ÅÄÜ»÷°ÜËý. £¨ÅÂÄã¼Åį£© I am sending a fax to let Cedars-Sinai verify Chen' MD If they kept on refering "Dr.Chen" and cannot give out a diploma or degree, Cedars-Sinai and Dr.Korenberg are cooperating on cheating public with their staff's qualification. £¨JRun£© Çë¡°¿Æѧʱ±¨¡±¼ÇÕß°ÑÕâ·â¶ÁÕßÀ´ÐÅת½»Ceidars-Sinai, UCLA Dear Science Times editor: I read the article about the acclaims made by the news spokenman of the Ceidars-Sinai Medical Center, UCLA, in responese to your journalist's questioning (Science Times, September 25th, 2000). I noticed that, in the spokeman's speaking, Ms. Xiaoning Chen has been mentioned as "Dr. Chen" for at least five times. Dr. Korenberg, Dr. Bruce Birren and Dr. H.£­U.Weier are also mentioned in the article, so, reasonably enough I assume Dr. Chen holds a doctoral degree as other people with this title do. To my surprise, in an reported conversation between Ms. Chen and a journalist from a Chinese newspaper (Youth News, August 24th, 2000) I read earlier time, when asked why didn't go further for a doctoral degree upon receiving her Master, Ms. Chen explained that she preferred to do some concrete work, which clearly delivering a message that she didn't pursue a graduate study towards a doctoral degree. For your reference, I listed the citated portion of the report(in Chinese) and its English translation as it follows, and the entirety of the article is attached to this mail too. (Chinese) ¡°1990ÄêÄãÔÚÂåÉ¼í¶´óѧ»ñµÃÁË˶ʿѧ룬Èç¹û¼ÌÐø¹¥¶Áϲ©Ê¿Ñ§Î»±ã¿ÉÌáÉý Ϊ½ÌÊÚ£¬ÄãΪʲôûÓмÌÐøÏÂÈ¥£¿¡± ¡°ÎÒÏë×öµãÊ£¬Ò²¾ÍÊÇÔÚÕâÆڼ䣬ÎÒºÍÈ«ÊÀ½çÊýʮλ¿Æѧ¼Ò£¬½¨ÆðÁËÈý´ó»ùÒò ¿â¡£²»¹ÜÄãÔÚÃÀ¹úÔõÑù³É¹¦£¬¼´±ãÈëÁËÃÀ¹ú¼®£¬Ä㻹ÊÇÖйúÈË£¬Èç¹û²»»Ø¹ú½ø Ò»²½·¢Õ¹ÊÂÒµ£¬Äã»á¾õµÃºÜ¿Éϧ£¬ÎÒÏë»Ø¹ú×ö³öµãÊÂÀ´£¬½«À´³É¹¦ÁË»¹¿ÉÒÔÔÙ Ïò¹úÍâÍƹ㡣¡± (English translation) (journalist): "Having received your Master degree at UCLA in 1990, if resumed syudy and obtained a doctoral degree, you may be prompted to a professor position, why didn't you?" (Xiao-ning Chen): "I want to do some concrete work, and since that time, I, together with tens of scientists all over the world, has built up the Big Three BAC Libs. No matter how successful you are in the United States, you are still a Chinese, though naturalized and became a US citizen, and would feel so regret for yourself if you didn't come back to further achieve your career success. I like to come back do something, and will apply it outside the country, if it is quite a success." Fraud academic credential is a serious issue in U.S. academic community, and most of the reputational institutions execute a 0-tolerance policy on this type of misconduct. On the other hand, if Ms. Chen does hold a doctoral degree, the reporting published on Youth News definitely misled public and applied a negative image to Ms. Chen's reputation, which is also unaccepted. The Ceidars-Sinai Medical Center, as the employer of Ms. Chen, may should take the responsibilty to help resolve this issue which confuses publics like me quite a lot. We wish honesty and courtesy are still respectful values and uncrossing lines in scientific community, and also, people's reputation should not be maliciously damaged by misleading publics on media. Yours truly, A reader 09/25/00 £¨°Íɽ£© I saw quite a few people with "adjunct professorships" having "professorship" on their personal homepage linked by the Cedars-Sinai's homepages too. It might be just webmaster's mistake. What I don't like is that CXN or his very "bright" husband took advantages of these and tried hard to fool chinese. I used to study at a program at UCLA medical school, Anybody who gained a ph.D from that program and worked at Ceder-Sinai can get an adjunct assistant professor title from UCLA medical school, Even if they don't do research at all. Another point is that if anybody gained B. of medicine can claim MD from UCLA(if UCAL officially say so after they know this event and give people an M.D. without a BS at medicine degree), I am going to try very hard to bring my two sisters to USA because they both have true degrees from quite prestigiou medical schools in China. And even better is that my parents should claim respects from Americans too (or just go back to China to collect respects from those people who trusted everything from USA:-), as they are physicians in China too and they are visiting me now at USA, And my father used his knowledge to help a few of my freinds(They are new Chinese Americans, I should remove "Chinese" to tell other people how good my father is -- to be honest, my father is good) here with accupucture and chinese medicine. Should I even try to apply for US jobs for my father? he might become a respectful US "M .D." and adjunct professor at East and West Medical Research Center at UCLA:-))) ) Who knows:---Haaaa... £¨nobody£© Ϊ³ÂСÄþµÄÊ£¬ÔÚ´ËÕýʽÏò·½ÐÖµÀǸ£¡ ¸ÕÔÚ»ªÔÀ¿´µ½ËýµÄÃÀ¹ú°ïÐ×µÄһͨ˵´Ç£¬Õâ³ÂСÄþ¾ø¶Ô ÊÇ°ïÃÀ¹úÈËÐÐÆ­µÄæ»×ÓÎÞÒÉ£¬Ðҵ÷½ÐÖÐÄÃ÷ÑÛÁÁ£¬·ñÔò ÓÖÒªÉϵ±£¬ÎÒ¼ºÔÚ»ªÔÀÏòÐÖ±íʾǸÒ⣬ԭÌùÈçÏ£º ****** Ô½ÌýÔ½·³£¬Õâ³ÂÆÅÔ­À´ÊÇÒ»¸ö°ïÑóÈËÐÐÆ­µÄ潼ˣ¡ ¿÷µÃ±¾³æÇ°¼¸Ì컹ÒÔΪËý»Ø¹úÊÇÕæµÄ£¬ÄǸö¿âÓбÈûÓк㬿ɸúÁÙ´²²îÊ®Íò°ËǧÀ ÏÖÔڴ󲿷ÝÐòÁж¼¿ÉÒÔÔÚPUBLIC DATABASEÕÒµ½£¬ÒªÓÃPCRµ÷³öÀ´Ò²²»·Ïʲô¾¢£¬Ã÷ °Ú×ÅÃÀ¹úÈËÊÇÏëÓÃÕâ¸öûÓÐÓõĶ«Î÷Õ¼¾ÝÖйú¿ÉÄܵijɹû£¬Õâ¸ö³Âæ»×Ó£¡ ±¾³æÔÚ´Ë×ðÖØÏò·½ÖÛ×ÓÐÖµÈ×îÏȽÒ¶³ÂµÄ¼¿Á©µÄÅóÓѵÀǸ£¬µ±Ê±³æÇé¿ö²»Ã÷£¬ÏÕЩ ½ÐÕâÅ®(˹)¸øÃÉÁË£¡ ******* ²¢¾Í´ËÊÂÏò·½ÐÖ±íʾ¾´Ò⣡ £¨´ó³æ£© µ½Ä¿Ç°£¬ÊDz»ÊÇÓаïÆ­µÄÆóͼ»¹Ã»ÈËÄÜŪ³öÖ¤¾ÝÀ´ ×îÆðÂ룬¹«¿ªÐź͸½Òé¿Í¹ÛÉÏÒ²ÔÚά»¤UCLAµÄÃûÓþ¡£ ³ÂµÄÐÐΪºÜÃ÷ÏÔËðº¦ÁËUCLAµÄÉùÓþ¡£ÒªÊÇUCLA¹Ù·½³öÀ´ Ö§³Ö³ÂÄDzſÉЦÄØ¡£ ÖÁÓÚÄǸöÖÐÐÄ£¬ÀëUCLA»¹²î×ÅÊ®Íò°ËǧÀïÄØ¡£ £¨Ì½ÌÖ£© ÓÐÀÍ¡¶¿Æѧʱ±¨¡·µÄ¼ÇÕß ¶Ô¡¶¿Æѧʱ±¨¡·¼ÇÕßµÄÌáÎÊ£¬°³¾õµÃÂåɼí¶Cedars£­SinaiҽѧÖÐÐÄÐÂÎÅ·¢ÑÔÈ˵Ļشð²»Íê Õû£¬»Ø±ÜÁËһЩÎÊÌâ¡£ ¼ÇÕߣºÈçºÎÆÀ¼Û³ÂÏþÄþŮʿ´øµ½ÖйúµÄÈý¸ö»ùÒò¿âµÄ¼ÛÖµ£¿ÓÐ ÈËÈÏΪËüÃÇÓÐÒ»¶¨¼ÛÖµ£¬µ«²¢²»È粩Äþ¹«Ë¾Ëù³ÆµÄÄÇÑù²»¿É¹ÀÁ¿£¿ Ò²ÓÐÈËÈÏΪ£¬ÈËÀà»ùÒò×éϸ¾úÈ˹¤È¾É«Ì壨BAC£©ÎÄ¿âÓü¸Ç§ÃÀÔª¾Í ÄÜÂòµ½¡£Èç¹ûÓÃÓÚ¿ÆѧÑо¿µÄ»°£¬ÕâÈýÖÖ»ùÒò¿â¿ÉÒÔÃâ·Ñ»ñÈ¡¡£Áí Í⣬³ÂÏþÄþŮʿ½«Æä´øµ½Öйú£¬ÊÇ·ñµÃµ½ÁËCedar£­SinaiҽѧÖÐÐÄ µÄÅú×¼?һЩ¿Æѧ¼ÒÈÏΪӫ¹âԭλÔÓ½»£¨FISH£©ÊÇÒ»ÖÖ¼òµ¥µÄ¼¼Êõ£¬ ¶Ô´ËÄãÃÇÓкÎÆÀ¼Û£¿ ·¢ÑÔÈË£º³ÂÏþÄþ²©Ê¿ÊÇCedars£­SinaiҽѧÖÐÐĺÍÂåÉ¼í¶¼ÓÖÝ´ó ѧ¶ù¿ÆϵµÄ³ÉÔ±£¬Ò²ÊÇһλÓгɾ͵ÄÑо¿Õߣ¬µ£ÈÎJulie korenberg ²©Ê¿Áìµ¼µÄCedars£­SinaiҽѧÖÐÐĵĸ±Ö÷ÈΣ¬ËýÔÚÎÒÃÇËùÌÖÂ۵Ļù Òò¿âµÄÑо¿ÖÐÆðµ½Á˹ؼü×÷ÓᣠÎÒÃÇÌÖÂÛµÄÓɳ²©Ê¿´øµ½ÖйúµÄÈýÖÖ»ùÒò²ÄÁÏ£¬°üÀ¨ÈËÀà»ùÒò ̽Õë¿â£¨The Integrated Mapped Human BAC Resource£¬ÕâÀï¼ò³ÆAÀà²ÄÁÏ£©¡¢Ð¡Êó»ùÒò¿Ë ¡¼°Ì½Õë¿â£¨The mouse molecular Cytogenetic?BAC? 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Èç¹ûÄãÒªÌø³öÀ´µ±»ù Òò»Êºó, ÄǾͲ»ÊÇ´ó×öÎÄÕÂÁË°É. Èëµ³²»»¹µÃ²é¹ý¼ÒÍ¥±³¾°Âð, ×ö»Êºó²é²éѧÀú¶¼²»ÐÐ? µ±»ÊµÛ²»´©Ò·þ¿ÉÒÔ, µ«·ÇÒªÉÏ´ó½ÖÉÏÓÎÐÐ, ÔÛ˵˵¾Í²»ÐÐÁËÂð? Ò²²»»áÏŵÃÈËÈ˶¼²»¸ÒÏ´ÔèÁË°É. ¾ÍÊǶÔѧÀú´ó×öÁËÎÄÕÂ, Ò²²»ÖÂÓÚË­¶¼²»¸Ò»Ø¹ú°É? ÎÒ¾ÍÄÇôһר¿Æ»¤Ð£Ñ§Àú, »ØÀ´Ò²¾ÍÊÇ »ì¿Ú·¹³Ô, ÄÄλҪ²é, ËäÈ»ÊdzԱ¥Á˳ŵÄ, ÎÒÒ²²»ÓÃÅÂѽ. ÄãÒ²±ð¼±µÃÓïÎÞÂ×´Î, Äã˵»°ºÜÇå³þ, ̬¶ÈºÜ¿Í¹Û, ÎÒÃǶ¼³ÐÈÏ»¹²»ÐÐô? ÄãȷʵÊÇÐij¦ºÃ , ¶¼ÔÚÌæ·½ÖÛ×Ó׿±, ÎÒÃǶ¼³ÐÈÏ»¹²»ÐÐô? ¸øÄą̃½×ÏÂ, Äã¸Ï½ô×ßÐв»ÐÐ? £¨Éñ£­¾­£© ½Ò¶ÕâÖÖÉÌÒµÐÔ³´×÷Æ­¾Ö²»ÐèҪȨÍþµÄ×ʸñ ÔÚÁÁÀöµÄ"ÊÀ½ç¶¥¼â¼¶¿Æѧ¼Ò"¼°"»ùÒò»Êºó"ÕÐÅÆÏÂ, ÊÇһ˫˫̰À· ÑÛ¾¦,¶¢×ÅÖйúÀÏ°ÙÐյĸոչÄÆðÀ´µÄÇ®°ü. Ö»ÒªÔÚÏà¹ØÁìÓòÀï ¹¤×÷¹ý»òÉÔ¾ßÕâ·½ÃæµÄרҵ֪ʶ,¾Í²»Äѽ«ÆäʶÆÆ. µ«Òª°ÑÕâЩ Æ­È˵Ķ«Î÷ÕÑʾÓëÊÀÈË,ÔòÐèÒª²»Ñ°³£µÄµ¨Ê¶,ÓÂÆøÓëÖÇ»Û. £¨Ðé¹È£© It Is Stupid for Cedar-Sinai To Endorse CXN Because of the endorsement, CS might be liable for CXN's misconduct. All the evidences suggest that CXN committed a fraud. If a victim was hurt by the fraud (say, the guy who invested 20 million RMB in CXN¡¦s company) and he brought a lawsuit against CXN in US, say in lala, he would be very likely to win. It is very possible, however, that CXN will be judgment-proof, i.e., have no money to satisfy the judgment. Neither CXN nor WHT would be put in jail, because it is a civil lawsuit. The victim would get nothing more than a paper. Hence, before filing a lawsuit, you¡¦d better find at least one deep-pocket as defendant, or co-defendant. Who is the potential deep-pocket defendant in the case? Kornberg, CS, and UCLA. Kornberg¡¦s pocket is not deep enough. It is difficult to pull UCLA in, because CXN is just an adjunct associate professor there. CS is the suitable deep-pocket defendant. Under what theory can the victim make CS a defendant? Agent-Principal. Under the law, CS as a principal might be responsible for the misconduct of CXN, CS¡¦s employee. CS has a powerful affirmative defense: it should not be held accountable for CXN¡¦s conduct, because CXN¡¦s conduct goes beyond the scope of employment. After all, CXN is employed to do research in lala, not to form a company in China. Now, the response of CS¡¦s public relation guy virtually takes away the valuable defense. It could be argued that CS is accountable, because the response is equivalent to an adoption of CXN¡¦s action. A principal will be accountable for its employee¡¦s beyond-scope action, if it adopts the action. Now CS could only argue that the response is also beyond the scope of employment. The real authority of CS, e.g., the president of CS, should be inquired whether the response is the opinion of CS. (Just as the pirates shouted to Aladin: ¡§Are you in, or out?!:-)ƒº The CS should respond to this inquiry. Silence in this situation would be considered as a constructive admission, since that guy claimed to be a representative of CS. Moreover, the response of the public relation guy includes something new, which is not disclosed by CXN. The new disclosure might further hurt CS. For example, the response alleged that CS has intellectual property rights over the B and C material. We want to know what kind of intellectual property rights CS has over the FISH libraries. There are four categories of intellectual property: patent, copyright, trademark, and trade secret. CS could hardly patent the libraries, because it is difficult for the alleged invention to meet the non-obviousness requirement in the proceedings of patent prosecution. Furthermore, patents and published pending application can be easily found in USPTO or IBM databases. I remember that several people searched and found nothing under the name of Korenberg or CXN. If it has an unpublished pending application, CS gets no right until the application is published or allowed. Copyright traditionally protects art works such as novels. Copyright is now stretched to cover software, but is not stretched to cover the stuff such as the FISH libraries yet. Trademark can not be used to protect the libraries in this case. In order to be a trade secret, the owner must to keep it as a secret. In the present situation, the libraries were published and used by several other groups, and thereby cannot be protected as trade secret. It is therefore very likely that CS has no intellectual property right over the libraries. Did CS lie to the public? Suppose CS has intellectual property rights over the libraries. In order to commercialize them, CXN needs to get assignment or license from CS. The public has right to know what benefit CS got from the deal, i.e., whether CS participated in CXN¡¦s venture. In judicial proceedings, only an injured person has standing to bring a lawsuit for remedies. Nobody claims to be hurt by CXN¡¦s conduct yet. CS and Korenberg are, however, also bound by professional ethics and responsibility of scientific research. In that proceeding, actual damages is not a pre-condition. Remember David Baltimore and Leo Hood? If CS and Korenberg endorse or even keep silence on CXN¡¦s conduct, they will likely be held liable. Accordingly, both CS authority and Korenberg owe the public an answer. ¡§Are you in, or out?!¡¨ £¨TaiGang£© ¿´µ½Îĸ´µÄÊ󱲡¢»ªÔÀµÄͯÖÇÃÇÒ»Ìý¡°ÃÀ¹úÖ®Òô¡±¾ÍÂÒÂʵÔÚºÃЦ ÓÐһλ»¹É¢·¢ÁËʲô¡°¾Ü¾øÓëÃÀ¹úÖ®ÒôºÏ×÷¡±ÉùÃ÷£¬ °Ñ×Ô¼ºµ±³Éʲô¶«Î÷ÁË£¿ÃÀ¹úÖ®ÒôÓÖûÀ´ÕÒËû£¬Õû ¸öÅú³ÂʼþҲû¼ûËûͶÈ룬ÄÇô×Ô×÷¶àÇé¸Éʲô£¿ ¸üÎ޳ܵĻ¹Ôìҥ˵·½ÖÛ×ÓͶ¿¿ÃÀ¹úÖ®Òô£¬ÓëÃÀ¹úÕþ ¸®ºÏ×÷ÔÆÔÆ¡£ Õâʱ¾À´ÊÇÃÀ¹úÖ®Òô×Ô¼ºÕÒÉÏÀ´µÄ£¬ÓÖ²»ÊÇÎÒÈ¥ÕÒ ËûÃÇ¡£ËûÃǼûÁËCedars-SinaiµÄ´ð¸´£¬²Å¾õµÃÕâÊ ÓÐÐÂÎżÛÖµ£¬ÏÈÈ¥ÕÒ³ÂÏþÄþ£¬±»¾Ü¾ø£¬ÔÙÀ´ÕÒÎÒÁË ½âÇé¿ö¡£ÎÒÒªÊÇÒ²¸úÄÇ°ïÊ󱲡¢Í¯ÖÇÃÇÒ»°ã°Ú³öÒ» ¸±¾Ü¾øºÏ×÷µÄ°®¹ú¼Ü×Ó£¬Æñ²»ÉÙÁËÒ»¸öÈÃÖйú¹«ÖÚÁË ½âÎÒÃǵĹ۵ãµÄ»ú»á£¿ÎÒÈç¹ûÒ²À´¸ö¾Ü¾ø»Ø´ðÎÊÌ⣬ Æñ²»ÈÃÈ˾õµÃÐÄÐ飨ÄÇʱÎĸ´¡¢»ªÔÀµÄÊó±²Í¯ÖÇÓÖ ÓбðµÄ»°ÒªËµÁË£©£¿¾ÍËãÎÒÒ»Éù²»¿Ô£¬È˼ÒÕæÏ뱨µÀ£¬ ²»Í¬Ñù¿ÉÒÔÅÜÐÂÓïË¿¿´ÓйزÄÁÏ×öÕªÒý£¿ÎÒÃÇ·¢µÄ Êǹ«¿ªÐÅ£¬¾ÍÊÇÄļÒýÌåÏëµÇ¶¼Äܵǣ¬ÎÞÐèÊÂÏÈ»ñ µÃÎÒÃǵÄͬÒâ¡£È˼ÒÒª±¨µÀ£¬ÄãÀ¹µÃס£¿ÃÀ¹úÖ®Òô¸ù ±¾¾Í²»¶ÔÃÀ¹ú¹úÄڹ㲥£¬Ëü±¨²»±¨£¬¶ÔÃÀ¹úÉç»áÓкΠӰÏ죿ÃÀ¹úÖ®ÒôµÄÖйúÌýÖÚ»¹ÊǺܶàµÄ£¬ÎÒÌáÇ°Ô¤¸æ һϣ¬²»¹ýÊÇÈùúÄÚµÄÍøÓÑÁôÐÄһϡ£ºÎ¿öÈ˼ÒÒ² û˵һ¶¨¾Í»á±¨µÀ¡£Ê²Ã´Ê±ºò±¨µÀÎÒÒ²²»ÖªµÀ¡£ 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According to the reply, the library A is an integrated mapped one from Kim and Shisuyan's BAC libraries, that means a library (?) of a lot of FISH localized BAC covering most regions of chromosomes. However, it is impossible to claim that this library belongs to Korenberg because BACs used are from others. She just mapped some of them to chromosome regions. 2. One serious issue is about Library C which is a random BAC library without any localization and insert information and which was donated by Chen to our country. That means she donated the most less useful library to the country and keep other useful one (Library A) for her company. I believe Library C is the remaining BAC clones from Kim and Shizuya's libraries after she integrated library A (i.e. about 7000 clones) from those libraries, or it is an entire library from the Research Genetics which contains her 7000 clones, too (but I think not very possible because she wants to keep those localized clones for making money). 3. I teached several granduate and undergraduate students to learn FISH and they mastered it in few days or one week. Of course, it will take time and experience to resolve problems like weak singal, high background, etc. If you work with FISH everyday, after 7 years you realized you are expert but you will find it is a simple one and you will find you are not qualitied in hte biology/g enetics field if you are restricted to it only, like Chen. Therefore you will not say you are top or really expert in the field but you can say you are FISH expert. If you want to apply for green card, your references, of course, will give your compliments. 4. BAC can be used in FISH right now in the field of identifying genes involved in chromosome aberrations (translocation, duplications, deletions). It is a good one to make rough search for location of breakpoints. It can be used as the first step in the whole project. 5. What one reference said about changing chromosome study means that Korenberg and Chen published two papers describing a combined method for gene localization(assignment) in Cytogenetics abd Cell Genetics and Genomics. They could localize small gene/clone to chromosome regions with their methods. FISH has limited sensitivity and is difficult to assign small clones (<2kb). They said they could assign 800bp clone to chromosome (but they were only in about 15% metaphase cells and it was a known gene). The most of work Chen did is with BAC, a very big clone (about 200-300kb), you could get strong signals even you close your eyes. Especially, now whole sequence of the genome is available, the localication function of FISH is not important anymore. 5. Even in USA FISH is not often used in prenatal diagnosis. If used it must combined with conventional chromosome analysis (i.e. cell culture, harvest, sliding, banding and analysis). BAC is more less used for clinical prenatal diagnosis. It is impossible to say 100% accuraty of FISH, because these are several factors that will affect FISH quality. Generally, FISH will be successful in about 70% prenatal studies (you get no signals or very weak signals in the remaining 30% cases because of cells and others). 6. Chen's problem is forgot where she is and where level she is. If she really know genetics/biology, she would not say she is top or what. Although I worked on similar field for several years and I have double, double and double first author papers published in better journals, I never think I am top, I only consider myself as a trained and experienced researcher in cytogenetics and molecular cytogenetics field of cancer. £¨qs£© those positive changes: 1. the newspapers in China stop bragging about ChenXN and will not brag about ChenXN in the future. 2. more and more people know who ChenXN is and what she has done. the message is spreading...it will take time. 3. Other ChenXN-like will become more carefullly, since they know people now are not gullible anymore, thanks for the internet. 4. many scientists in China already know about ChenXN incident, and feel encouraged by the letter. 5. you will see more articles on ChenXN incident in the future in China's media. just be patient, this incident is not over yet. 6. Jin Li or Jin li-like dares not to stand out as he initially did. I am sure no one else will have gut to stand out for her. 7. ChenXN does not have any credibility anymore. If you read Jin li's response in Science times, he neither call ChenXN professor nor Dr sth. can you see that? 8. Berning has quietly removed the articles from their homepage, and Wang CEO's lost his credibility too. £¨pro£© »¥Á¬Íø ´Ó×î½üµÄ³ÂÏþÄþʼþ£¬Ö캣¾ü²¡ÊÅ£¬µ½°ÂÔË»áµÄÍõÀöƼ¶á½ð·ç²¨£¬ÈËÃÇ ²»ÄѸÐÊܵ½»¥Á¬ÍøµÄ×÷ÓÃȷʵÊDZðµÄýÌåËùÎ޿ɱÈÄâµÄ£¬Ê¹µÃijЩÏë͵ ͵ÃþÃþ×öµãʲôµÄÈ˾õµÃºÜ²»×ÔÔÚ£¬Ò»µ©±»³³µ½ÍøÉÏ£¬¼¸ºõÕâÊÀ½çÉÏËù ÓеÄÈ˶¼ÓпÉÄܶÔËûÃǽøÐÐÆÀÂÛ£¬ÕæÀíµ±È»×îÖÕ»áÕ¾ÔÚ´ó¶àÊýÈËÄDZߡ£ ÎÒÊÇ´ÓÅóÓÑÄÇÀïÌý˵µÄ¶ÁÊ飬À´ÕâÀïÒ²¾Í1¸ö¶àÔ£¬µ«Ã¿Ìì±ØÐëÀ´ÕâÀï ¿´¿´³ÂÏþÄþ±»¾¾³öÀ´Ã»ÓУ¬Ö캣¾üÕæµÄËÀÁË£¬»¹ÊÇ´ó¼ÒÓÖÔÚ̸ÂÛÁíÒ»¸ö »°Ì⣬ÈçһλÍøÓÑËùÑÔ£¬·½ÖÛ×ÓÊÇ·´Î±¿ÆѧµÄÒ»ÃæÆìÖÄ£¬ÓÐÈËËäÈ»ºÞÖ® Èë¹Ç£¬»¹ÊÇÉá²»µÃÕâÀï¡£ÆäʵÕâλÅóÓÑÊÇÉá²»µÃÕâÀïµÄ´ó¼Ò£¬²»ÊÇ·½Ò» ¸öÈË¡£ £¨mike5£© ×íÎÌÖ®Òâ ÎÊÌâÆäʵҲºÜ¼òµ¥¡£Èç¹û¸Ã¶«Î÷ºÜÓмÛÖµ£¬ÄÃÁËÒÔºóÄã¸ÒÈç´ËÉùÕÅÂð£¿ÃÀ¹úÈË(³ÂÒ² ÊÇ)»á·Å¹ýÄãÂð£¿ÀîÎÄºÍ Ê¼þ»¹Ã»Íê½á¡£·´Ö®£¬ÔòË­¶¼ÄÜÄõ½£¬×î¶à»¨Ò»µãÇ®¾ÍÊÇ ÁË¡£ÖµµÃÕâôÕÅÑïÂ𣿴ó¼ÒÖ»ÒªÓÃÄÔÏëÒ»Ïë¾ÍÃ÷°×¡£ÎÊÌâÊÇÖйúµÄ¼ÇÕßΪʲô»áÈç ´Ë±¨µÀ£¿Æäʵ£¬ÔÚÖйú£¬×ö¼ÇÕߺÜÈÝÒ×£¬Êܵ½ÑûÇëºó£¬È¥±¨µÀ¾ÍÊÇ£¬»á¸øÄãÒ»¸öÐÅ ·â£¬ÀïÃæ×°ºÃÁËÐÂΟå¼þ£¬µ±È»»¹ÓÐһЩÆäËû¶«Î÷£¬¹é¸öÈ˵ġ£È»ºó³Ô³Ô·¹£¬´µ´µ Å££¬¾Í¿ÉÒÔ»ØÈ¥½»²îÁË¡£´ËÊÂÄֵ÷зÐÑïÑÕýºÃ´ïµ½Á˳µÄÕÉ·òµÄÄ¿µÄ£ºÌæÆ乫 ˾×ö¹ã¸æ¡£ÊÔÏëÏ룬һ°ã¹ã¸æÒª´ïµ½Èç´ËЧ¹û£¬µÃ»¨¶àÉÙÇ®£¿ÁíÍâÒ»¸ö¾ÍÊÇΪ³ÂÑï Ãû£¬Ä¿µÄÒ²´ïµ½ÁË¡£ £¨ôùûè룩 ¡ª¡ª¡ª¡ª¡ª¡ª¡ª¡ª¡ª¡ª¡ª¡ª¡ª¡ª¡ª¡ª ¡¾ÐÂÓïË¿µç×ÓÎÄ¿â(www.xys.org)(www.xys2.org)¡¿