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浙大李连达院士的研究成果 = 剽窃 + 造假 + 一稿多投

作者：Milli
 
　　又发现李连达院士小组一篇造假文章，这次直接被杂志社宣布撤回：He H, 
Shi M, Zeng X, Yang X, Yang J, Wu L, Li L.  Retracted Decreased 
FKBP12.6 expression and enhanced endothelin receptor signaling 
associated with arrhymogenesis in myocardial infarction rats.   
Phytother Res. 2008 Aug;22(8):1115-24.

　　链接：
http://www3.interscience.wiley.com/journal/119881937/abstract

　　摘要处写道：Scientific Deception: Retraction of a Fraudulent Paper 
Andrew Coats Elizabeth M. Williamson We the editors of the 
International Journal of Cardiology and Phytotherapy Research 
regretfully report a case of scientific fraud. We have been made aware 
that two manuscripts published around the same time contain similar 
figures and tables. Upon further investigation the manuscript 
published in Phytotherapy Research 1 appears to have included falsely 
reproduced experiments with no acknowledgement of original source data 
and has consequently been retracted. The manuscript published in the 
International Journal of Cardiology 2 stands and there is no criticism 
of the authors of this paper. 1. He H, Shi M, Zeng X, Yang X, Yang J, 
Wu L, Li L. Decreased FKBP12.6 expression and enhanced endothelin 
receptor signaling associated with arrhymogenesis in myocardial 
infarction rats. Phytother Res. 2008 Aug;22(8):1115-24. Doi: 
10.1002/ptr.2470 2. Zhang Y, Huang ZJ, Dai DZ, Feng Y, Na T, Tang XY, 
Dai Y. Downregulated FKBP12.6 expression and upregulated endothelin 
signaling contribute to elevated diastolic calcium and 
arrhythmogenesis in rat cardiomyopathy produced by l-thyroxin. 
International Journal of Cardiology, [Epub ahead of print] 
Doi:10.1016/j.ijcard.2008.05.018

　　可以看出：1，首先这篇文章是剽窃了别的实验室的数据；2，用剽窃来的数
据改成自己研究的治疗药物的数据发表。

　　这显然是剽窃和造假。下面列出了所有新语丝上涉及李连达研究小组的论文
一稿多投，剽窃，造假的文章，加上上面一篇，一共13篇文章，中文、英文都有。
发表时间都在2006年以后。

　　一个研究组在3年时间里有这么多的文章有问题，李院士一点都不知道？通
讯作者一点都不知道？

　　浙大还要沉默到什么时候？中国工程院还要沉默到什么时候？

1, He HB, Yang XZ, Shi MQ, Zeng XW, Wu LM, Li LD.  Comparison of 
cardioprotective effects of salvianolic acid B and benazepril on large 
myocardial infarction in rats.  Pharmacol Rep. 2008 
May-Jun;60(3):369-81.
2, He H, Shi M, Yang X, Zeng X, Wu L, Li L.  Comparison of 
cardioprotective effects using salvianolic acid B and benazepril for 
the treatment of chronic myocardial infarction in rats. Naunyn 
Schmiedebergs Arch Pharmacol. 2008 Sep;378(3):311-22. Epub 2008 May 24
3, He H, Shi M, Yang J, Zeng X, Qiao H, Wu L, Li L.  Cardioprotective 
effect of salvianolic acid B on large myocardial infarction mediated 
by reversing upregulation of leptin, endothelin pathways, and abnormal 
expression of SERCA2a, phospholamban in rats.  J Ethnopharmacol. 2008 
Jun 19;118(1):35-45. Epub 2008 Mar 16.
4,1: Zeng X, He H, Yang J, Yang X, Wu L, Yu J, Li L.
 Temporal effect of Guanxin No. 2 on cardiac function, blood viscosity 
and angiogenesis in rats after long-term occlusion of the left 
anterior descending coronary artery. J Ethnopharmacol. 2008 Aug 
13;118(3):485-94.
5, Wu L, Qiao H, Li Y, Li L.   Protective roles of puerarin and 
Danshensu on acute ischemic myocardial injury in rats.
6, Wu L, Qiao H, Li Y, Li L.   Cardioprotective effects of the 
combined use of puerarin and Danshensu on acute ischemic myocardial
7, Niu YP, Wu LM, Jiang YL, Wang WX, Li LD.   Beta-escin, a natural
triterpenoid saponin from Chinese horse chestnut seeds, depresses 
HL-60 human leukaemia cell proliferation and induces apoptosis.  J
Pharm Pharmacol. 2008 Sep;60(9):1213-20.
8, Niu YP, Li LD, Wu LM.Beta-aescin: a potent natural inhibitor of 
proliferation and inducer of apoptosis in human chronic myeloid
leukemia K562 cells in vitro. Leuk Lymphoma. 2008 Jul;49(7):1384-91.
9, X.-H. Zhou, L. Han, W. Wang, L.-D. Li, L.-M. Wu, H.-X. Qiao, J.
Yang，and X.-F. Zhou.Subacute Bloodstream Blockade Effect by 
Supercontraction of Spider Silk。Methods and Findings in Experimental
and Clinical Pharmacology. 2006;28(10):713-717
10, 李连达，周晓辉，吴理茂，韩蕾，李贻奎，王炜，蛛丝对股动脉血流亚急性
阻断作用的研究，《中华中医药学刊》2008年 26( 5):901-904
11, X.-H. Zhou, L.-D. Li, L.-M. Wu, W. Wang, L. Han, J. Yang, H.-X. 
Qiao and X.-F. Zhou. A Minimally Invasive Model of Myocardial
Infarction Made by Video-Assisted Thoracoscopic Surgery. Methods and 
Findings in Experimental and Clinical Pharmacology.2007，29（4）：
283-290
12, 李连达，周晓辉，吴理茂，韩蕾，李贻奎，王炜，乔洪翔，杨俊，周雪芳，
应用电视辅助胸腔镜制作慢性微创心肌梗死模型的研究，《中华中医药学
刊 》2008年 26(3):453-456.

(XYS20081211)

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