it may more sense by reading this and the one below

送交者: blackbox 于 2012-01-13, 18:18:30:

回答: Questionare is OK, for the endpoint score 由 cornbug 于 2012-01-13, 16:41:34:

regarding the additional measures

looks like you will have a longitudial analysis for score change and survival analysis for symptoms developed during the follow-up period.