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送交者: 猎人 于 2012-01-13, 12:35:47:

回答: RCT design to test the effectiveness of an intervention 由 cornbug 于 2012-01-13, 11:31:10:

1, This is a one-arm study. You may need a control arm.
Without one, this may not be called RCT
2, I don't think ANOVA is applicable here. I don't know what to use to analyse your data. Linear regression? Better speak to statistician
3, This is not a survival study for sure. Survival study is misnomer. It is a study of non-reccuring event, such as life/death. It is not limited to life/death, as long as it is non-recurring. Yours is not.
4 a blind scorer will not solve bias in your test. It is the nature of this type of study. Make sure your questionaire is a quantatative one. Sounds like yours is. If you can find way to blind subjects, that will be ideal.
5 this is more of a QoL study.
6 again get a control group.

So far for now. On a cell phone, hard to read and type.




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