被砍掉的可以添加到附录里:)


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送交者: 羽矢 于 2010-11-07, 10:11:58:

回答: 感觉公开信稿件太长、太杂,试着给砍了一些 由 eddie 于 2010-11-07, 09:12:25:

病例类型人数、术前余尿:

1998 abstract
http://xysblogs.org/wp-content/blogs/107/uploads/1998xiao14sci.gif
Xiao CG., Godec, CJ., Du, MX., Dai, C., and Xiao, Q.,: A new procedure to restore bladder functions after SCI: Preliminary report on 14 patients. J.Urol. 159:304A, 1998

We have performed this procedure on 14 SCI patients since 1995 to try to restore controllable voiding....

Of 6 patient with hyperreflexic badder, 5 had successfull recovery of bladder function. They are able to void by initiating the skin-CNS-Bladder relex, which became functional from the 10th to 12th month postoperatively. Residual urine decreased from 300 ml to 31 ml in average, and no UTI occurred since the sixth month postsurgically. CMG study documented the changes of the bladder from hyperreflexia and high pressure to relatively normal.... Among 8 patients with areflexic bladder, 3 showed remarkable recovery and 1 had patial recovery.


2003 paper:
Xiao CG, Du M-X, Dai C et al: An artificial somaticcentral nervous system-autonomic reflex pathway for controllable micturition after spinal cord injury: preliminary results in 15 patients. J Urol 2003; 170: 1237.

A total of 15 male volunteers with hyperreflexic neurogenic bladder...

Of the 15 patients 10 (67%) regained satisfactory bladder control within 12 to 18 months after VR micro anastomosis. Average residual urine decreased from 332 to 31 ml and
urinary infection as well as overflow incontinence disappeared. Urodynamic studies revealed a change from detrusor hyperreflexia with DESD and high detrusor pressure to almost normal storage and synergic voiding without DESD.

After successful experiments in animals, clinical trial was started in 1995. We report results in the first 15 patients with SCI.


http://www.hlhl.org.cn/news/findnews/showsub.asp?id=476
1995年开始临床应用研究,首期治疗截瘫病人14例,术后经2.5~3.5年随访,结果6例高反射性神经原性膀胱患者中,5例恢复膀胱储尿排尿功能。平均残余尿由317毫升下降到29毫升,术后6个月起即无泌尿系统感染复发。1例因其他原因治疗失败。另8例无反射性神经原性膀胱患者中,术后5例完全恢复膀胱储尿排尿功能,1例部分恢复,平均残余尿由288毫升降到32毫升,1例因瘢痕过多放弃手术,1例失去随访。所有膀胱功能恢复者,其直肠功能(大便排泄)亦恢复正常。




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