2007 review article on 上呼吸道感染的研究


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送交者: james_hussein_bond 于 2008-12-31, 22:16:47:

http://www.ingentaconnect.com/content/iuatld/ijtld/2007/00000011/00000009/art00002
引用:
Exposure to cold and respiratory tract infections [review article]

Mourtzoukou, E.G.1; Falagas, M.E.2

The International Journal of Tuberculosis and Lung Disease, Volume 11, Number 9, September 2007 , pp. 938-943(6)

Abstract:
There is a constant increase in hospitalizations and mortality during winter months; cardiovascular diseases as well as respiratory infections are responsible for a large proportion of this added morbidity and mortality. Exposure to cold has often been associated with increased incidence and severity of respiratory tract infections. The data available suggest that exposure to cold, either through exposure to low environmental temperatures or during induced hypothermia, increases the risk of developing upper and lower respiratory tract infections and dying from them; in addition, the longer the duration of exposure the higher the risk of infection. Although not all studies agree, most of the available evidence from laboratory and clinical studies suggests that inhaled cold air, cooling of the body surface and cold stress induced by lowering the core body temperature cause pathophysiological responses such as vasoconstriction in the respiratory tract mucosa and suppression of immune responses, which are responsible for increased susceptibility to infections. The general public and public health authorities should therefore keep this in mind and take appropriate measures to prevent increases in morbidity and mortality during winter due to respiratory infections.


结论:比2001年的文章更广泛。吸入冷空气,降低体表温度,或降低体温都会减弱抵抗力,增加得感冒的机会,加剧症状,增加死亡率。这可是人命关天的大事。

BTW, in the abstract, "most of the available evidence from laboratory and clinical studies suggests that" means that this is nearly a scientific consensus.




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