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送交者: Yush 于 2008-09-18, 11:54:20:

回答: 陈竺已蜕变成一个无耻政客 由 dopi 于 2008-09-18, 11:24:53:

“陈君石院士以100倍推算到人体安全性的算法”,版主说是“毒物学通用的做法”
http://www.cfsan.fda.gov/~dms/melamra.html
The point of departure (POD) is the NOAEL of 63 mg/kg/day from the rodent subchronic bioassay. This POD was then divided by two 10-fold safety/uncertainty factors (SF/UF) to account for inter- and intra-species sensitivity, for a total SF/UF of 100. The resulting Tolerable Daily Intake (TDI) is 0.63 mg/kg bw/day.




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