送交者: xj 于 2005-10-13, 10:10:37:
Objective: Despite that many effective antihypertensive drugs are available, only 6.16% of hypertensive patients have satisfactorily controlled their blood pressure. This study examines the reasons for the low success rate among hypertensive patients.
Subjects and methods: Among 1083 hypertensive patients treated by the Department of cardiology, XX hospital from January, 2000 to December, 2001, 833 cases had complete follow up information and were included in this study. Their ages ranged from 32 to 88 years, with the mean age of 53.5 years and standard deviation (SD) 10.5 years. The treatments were either to increase the original drug doses (246), or to add another antihypertensive drug (587).
Results: the means (±SD) of baseline systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 172.3 ±22.4 mmHg and 108.6 ±13.3 mmHg. After treatment, the means of SBP/DBP were 141.9 ±15.4 mmHg /90.7 ±11.2 mmHg, with average decreases of 30.4/17.9 mmHg (p<0.005). Overall, 382 patients successfully controlled their blood pressure (success rate: 45.9%). However, 548 patients failed to fully comply with treatment plans (65.8%). Reasons were the misunderstanding of treatments, financial difficulties, unsatisfactory blood pressure control, inconvenience in taking drugs, and miscommunication with physicians.
Conclusion: strategies to overcome noncompliance barriers will significantly improve the success rate in treating hypertension.