感谢瘪三给我保存了一贴


所有跟贴·加跟贴·新语丝读书论坛

送交者: TIDAn 于 2013-01-10, 12:14:43:

回答: 由 asasasa 于 2013-01-10, 03:56:25:

http://xys.org/forum/db/10/193/198.html
假设是把所有患有与肾有关的疾病的人按疾病分组后每组里因AA致病的比例大致不变 譬如以下的3%与3.7%就是个证明
J Natl Cancer Inst 2010;102:179–186
引用:
In conclusion, having been prescribed more than 60 g of Mu Tong or more than 150 mg aristolochic acid from Chinese herbal products was associated with an increased risk of developing urinary tract cancer. The linear dose–response relationship between the estimated level of aristolochic acid and urinary tract cancer might be useful for considering a complete ban, or for establishing limits, on the consumption of herbal products and/or herbs that contain low amounts of aristolochic acid (41). Care must still be taken for prescribing doses less than 60 g of Mu Tong or 150 mg of aristolochic acid because there might be no threshold dose under a linear dose–response relationship and given recent evidence for an increased risk of chronic kidney disease associated with a prescribed dose of 30–60 g of Mu Tong (34). In this study, from 2001 to 2002, there were 118 new cases of urinary tract cancer in Taiwan associated with the ingestion of more than 60 g of the Chinese herb Mu Tong, which represents 3% of all new patients with urinary tract cancer.

American Journal of Kidney Diseases, Vol 55, No 3 (March), 2010: pp 507-518

引用:
In conclusion, herbal products containing significant amounts of aristolochic acid, including Mu Tong and Fangchi, contributed to the high incidence and prevalence of CKD or ESRD in Taiwan from 1997-2002. Using >60 g of Mu Tong or Fangchi from herbal products was associated with an increased risk of developing ESRD. In 1998-2002, there were 949 new cases of ESRD in Taiwan in which the patient ever consumed Fangchi or Mu Tong before the diagnosis of CKD, representing 3.7% of all new patients with ESRD.




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