送交者: BOQ 于 2006-5-09, 04:31:46:
J. Am. Chem. Soc., 124 (23), 6792 -6792, 2002. JACSAt 10.1021/ja025103r S0002-7863(02)05102-8
Web Release Date: May 18, 2002
Copyright © 2002 American Chemical Society
Total Synthesis of Kaitocephaln, the First Naturally Occurring AMPA/KA Receptor Antagonist [J. Am. Chem. Soc. 2001, 123, 9706-9707].
Dawei Ma* and Jiade Yang
Page 9707, Scheme 3: The last step should give a mixture of (2R,3S,4R,7R,9S)- and (2S,3S,4R,7R,9S)-isomers in a ratio of about 1/1 via the unexpected racemization. The detailed mechanism will be discussed elsewhere. The configuration of kaitocephalin was revised as the (2R,3S,4R,7R,9S) form (Okue, M.; Kobayashi, H.; Shin-ya, K.; Furihara, K.; Hayakawa, Y.; Seto, H.; Watanabe, H.; Kitahara, T. Tetrahedron Lett. 2002, 43, 857-860).05/18/2002
* In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.