送交者: sisi1 于 2006-3-10, 15:03:32:
http://www.nature.com/ncb/journal/v8/n3/full/ncb1377.html
Xu, Y., Zhu, K., Hong, G., Wu, W., Baudhuin, L. M., Xiao, Y. & Damron, D. S. Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor. Nat. Cell Biol. 2, 261–267 (2000)
We wish to retract this paper due to concerns about data presented in Fig. 1. The principal data in question are the calcium profile data in Fig. 1a. These data were obtained by Dr. Kui Zhu (joint first author), at the time a research fellow in the laboratory of Dr. Yan Xu (senior author), in the Lerner Research Institute of the Cleveland Clinic Foundation. The original data used to compose Fig. 1 cannot be located. The first peaks in the upper and lower panels of Fig. 1a show high homology, although different ligands were used in the two experiments.
An institutional inquiry panel and an investigation panel were formed to determine the possibility of misconduct on the part of Dr. Kui Zhu in two related papers (Kabarowski, J. H. et al. Science 293, 702–705 (2001) and Zhu, K. et al. J. Biol. Chem. 276, 41325–41335 (2001). The committee found Dr. Zhu guilty of data fabrication and scientific misconduct related to these two publications. The very strong similarity of the two traces in Fig. 1 and the lack of original data suggest that similar misconduct occurred by Dr. Zhu in this Nature Cell Biology publication.
Owing to the serious concerns about the validity of the data published in the paper, we would like to retract this paper. We deeply regret any inconvenience this publication has caused for others. All authors, apart from Dr. Kui Zhu, have signed this retraction. Dr. Zhu did not return a signature.